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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
18.48
Human Site:
Y285
Identified Species:
31.28
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
Y285
S
K
L
T
P
T
L
Y
V
G
K
Y
S
T
S
Chimpanzee
Pan troglodytes
XP_511585
968
108684
L289
S
F
E
E
V
I
N
L
V
D
Q
T
S
E
N
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
Y378
S
K
L
T
P
T
L
Y
V
G
K
Y
S
T
S
Dog
Lupus familis
XP_853409
975
109686
Y285
S
K
L
T
P
T
L
Y
V
G
K
Y
S
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
Y287
S
K
L
T
P
T
L
Y
V
G
K
Y
S
T
S
Rat
Rattus norvegicus
XP_573211
965
109012
S282
Y
V
G
K
Y
S
T
S
L
Y
A
S
P
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
S280
A
V
V
P
R
G
S
S
F
P
L
L
E
G
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
Y290
T
H
L
L
P
S
L
Y
V
G
K
H
V
T
G
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
V279
H
S
T
K
T
Q
L
V
P
T
L
Y
V
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
V281
L
S
V
P
F
T
T
V
S
D
E
A
Y
Q
A
Honey Bee
Apis mellifera
XP_392044
968
110555
N280
S
V
A
D
E
T
L
N
L
I
L
K
R
F
A
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
N293
P
Q
T
T
S
L
T
N
Q
F
F
P
A
L
F
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
I305
K
L
V
P
T
L
Y
I
G
D
Y
P
S
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
F285
I
V
I
G
K
T
I
F
E
L
G
I
H
S
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
20
100
100
N.A.
100
0
N.A.
0
N.A.
53.3
13.3
N.A.
6.6
20
6.6
6.6
P-Site Similarity:
100
33.3
100
100
N.A.
100
20
N.A.
13.3
N.A.
73.3
13.3
N.A.
26.6
33.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
0
0
8
8
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
22
0
0
0
0
0
% D
% Glu:
0
0
8
8
8
0
0
0
8
0
8
0
8
8
0
% E
% Phe:
0
8
0
0
8
0
0
8
8
8
8
0
0
8
8
% F
% Gly:
0
0
8
8
0
8
0
0
8
36
8
0
0
22
8
% G
% His:
8
8
0
0
0
0
0
0
0
0
0
8
8
0
0
% H
% Ile:
8
0
8
0
0
8
8
8
0
8
0
8
0
0
0
% I
% Lys:
8
29
0
15
8
0
0
0
0
0
36
8
0
0
8
% K
% Leu:
8
8
36
8
0
15
50
8
15
8
22
8
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
8
15
0
0
0
0
0
0
8
% N
% Pro:
8
0
0
22
36
0
0
0
8
8
0
15
8
0
8
% P
% Gln:
0
8
0
0
0
8
0
0
8
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
43
15
0
0
8
15
8
15
8
0
0
8
43
15
29
% S
% Thr:
8
0
15
36
15
50
22
0
0
8
0
8
0
36
0
% T
% Val:
0
29
22
0
8
0
0
15
43
0
0
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
8
36
0
8
8
36
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _